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Effective role of narrow band-UVB in immunological changes of VZV:T-cells response

 
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Research Article 
dx.doi.org/10.18081/2333-5106/016-3/61-74
American Journal of BioMedicine Volume 4, Issue 3, pages 61-74
Received September 05, 2015; accepted January 21, 2015; published March 26, 2016 

Phillip B. Gaugera, Matthew A. Angela, Kristina Ballengerb, Brian P. Lazzaroamail of corresponding author

Abstract

Varicella-zoster virus (VZV) infection often observed in children and usually lasts a short time. Its remains dormant in the nervous system and can reactivate causing herpes zoster (HZ). The objective of this study is to investigate the effective role of nb-UVB, on immunological response of T-regulatory cells via different types of HZV transcription factors and possible pathological mechanism. Together these data confirmed that the using of nb-UVB in treatment of VZV is associated with T-regulatory cells response changes and attenuated VZV infection.

Keywords: Varicella-zoster virusnb-UVBHerpes zoster; T-regulatory cells

Copyright © 2016 by The American Society for BioMedicine and BM-Publisher, Inc.

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