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Assessment of postmenopausal bleeding: a cohort case study

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Azhar Mousa Al-Turiahi¹, Fawz Alla El-Dine, Sarah Hamza Herez

 

Abstract

The objective of this study is to assessment the postmenopausal bleeding (PMB), and investigated their causes, correlation with variable socio-demographic status. A 140-women complaining of PMB were enrolled in this study, each patient had a proper questionnaire filled in, with appropriate investigations that included; ultrasonography, Pap smear, colposcopy with cervical biopsy and endometrial curettage to take endometrial biopsy for histopathology. Nearly all cases were married 135 (96.4%), most of them were obese and overweight 97(69.3%), 43(30.7%) were having normal body mass index. Various etiology of PMB were found in this study; endometrial cancer (9.3%), cervical cancer (0.7%), atrophic endometritis (7.1%), atrophic vaginitis (2.8%), endometrial hyperplasia (45%), Cervicitis-CIN (15.7%), cervical polyp (12.8%), and endometrial polyp (18.6%). Bleeding from benign causes and of endometrial cancer occurs at fifth decade and sixth decade of life, while from cervical cancer occurs at seventh decade. The pattern of PMB; mild bleeding significantly higher in cervicitis-CIN; moderate bleeding more in endometrial polyp and significantly higher than mild and sever bleeding; while severe bleeding was significantly associated in endometrial cancer. Duration of PMB had a vast range (4 days to 5 years). 24.83% of cases had prolonged bleeding > 6months, (48.7%) with endometrial hyperplasia, (12.8%) had endometrial cancer. The endometrial cancer present in 10% of the patients with recurrent PMB.

Keywords: Postmenopausal bleeding; Endometrial cancer; Colposcopy

Copyright © 2016 by The American Society for BioMedicine and BM-Publisher, Inc.

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Research Article
dx.doi.org/10.18081/2333-5106/016-7/263-280
American Journal of BioMedicine Volume 4, Issue 7, pages 263-280
Received February 08, 2016; accepted June 29, 2016; published July 09, 2016

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Article outline

  1. Abstract
  2. Keywords
  3. Introduction
  4. Materials and methods
  5. Results
  6. Discussions
  7. Acknowledgements
  8. References

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