Advertisement

Adult cerebellar glioblastoma: case report and review of the literature

 
crossMark
 
Research Article 
dx.doi.org/10.18081/2333-5106/016-3/42-53
American Journal of BioMedicine Volume 4, Issue 3, pages 42-53
Received October 03, 2015; accepted February 15, 2016; published March 18,  2016

 Gabriel Castelluccioamail of corresponding author, Gonzalo Bertullob, Rafael De Armasc

Abstract

Glioblastoma is the most common and malignant primary brain tumor but its occurrence in the cerebellum is very rare. Giving its low occurrence the treatment modalities and outcome of this glioblastoma location are still poorly understood. We present the case of an adult woman with a cerebellar glioblastoma treated at the Clinical Hospital of Montevideo, and we perform a non-systematic review of the literature concerning the clinical, radiological and pathological features of this tumor, as well as its treatment modalities, prognostic factors and outcome.

Keywords: Cerebellar glioblastoma; Treatment modalities; Prognostic factors; Outcome

Copyright © 2016 by The American Society for BioMedicine and BM-Publisher, Inc.

Article citationReferencesFull-Text/PDFFeedback
The citation data is computed by the following citation measuring services:

Google scholarcitedby

References

1. Demir MK, Hakan T, Akinci O, Berkman Z. Primary cerebellar glioblastoma multiforme. Diagn Interv Radiol 2005;11:83-86. [PubMed]

2. Lakičević G, Arnautović K, Mužević D, Chesney T. Cerebellar glioblastoma multiforme presenting as hypertensive cerebellar hemorrhage: case report. J Neurol Surg Rep 2014;75:e117-e121. [Abstract/Full-Text]

3. Grahovac G, Tomac D, Lambasa S, et al. Cerebellar glioblastomas: pathophysiology, clinical presentation and management. Acta Neurochir (Wien) 2009;151:653-657. [PubMed]

4. Linsenmann T, Monoranu CM, Vince GH, et al. Long-term tumor control of spinal dissemination of cerebellar glioblastoma multiforme by combined adjuvant bevacizumab antibody therapy: a case report. BMC Research Notes 2014;7:496. [PubMed]

5. Gopalakrishnan CV, Dhakoji A, Nair S, Menon G, Neelima R. A retrospective study of primary cerebellar glioblastoma multiforme in adults. Journal of Clinical Neuroscience 2012;19:1684-1688. [Abstract/Full-Text]

6. Urbańska K, Sokołowska J, Szmidt M, Sysa P. Glioblastoma multifo-rme: an overview. Contemp Oncol (Pozn) 2014;18(5):307-312. [PubMed]

7. Stark AM, Maslehaty H, Hugo HH, Mahvash M, Mehdorn HM. Glioblastoma of the cerebellum and brain stem. Journal of Clinical Neuro-science 2010;17:1248-1251. [PubMed]

8. Montaudon M, Latrabe V, Iriart X, Caix P, Laurent F. Congenital coronary arteries anomalies: review of the literature and multidetector computed tomography (MDCT)-appearance. Surg Radiol Anat 2007;29(5):343-55. [PubMed]

9. Hess KR, Broglio KR, Bondy ML. Adult glioma incidence trends in the United States, 1977-2000. Cancer 2004;101:2293-2299. [PubMed]

10. Modan B, Wagener DK, Feldman JJ, Rosenberg HM, Feinleib M. Increased mortality from brain tumors: a combined outcome of diagnostic technology and change of attitude toward the elderly. Am J Epidemiol 1992;135:1349-1357. [PubMed]

11. Adams H, Chaichana KL, Avendaño J, Liu B, Raza SM, Quiñ-ones-Hinojosa A. Adult cerebellar glioblastoma: understanding survival and prognostic factors using a population-based database from 1973 to 2009. World Neurosurgery 2013;80(6):e237-e243. [PubMed]

12. Utsuki S, Oka H, Miyajima Y, Kijima C, Yasui Y, Fujii K. Adult cerebellar glioblastoma cases have different characteristics from supratentorial glioblastoma. Brain Tumor Pathol 2012;29:87-95. [PubMed]

13. Jing X, Shen G, Su M, Tian R, Jia Z. Primary glioblastoma of the cerebellar vermis: A case report. Onc-ology Letters 2015;10:402-404. [PubMed]

14. Tsung AJ, Prabhu SS, Lei X, Chern JJ, Benjamin N, Shonka NA. Cerebellar glioblastoma: a retrospective review of 21 patients at a single institution. J Neurooncol 2011;105: 555-562. [PubMed]

15. Babu R, Sharma R, Karikari IO, Owens TR, Friedman AH, Adamson C. Outcome and prognostic factors in adult cerebellar glioblastoma. Journal of Clinical Neuroscience 2013;20:1117-1121. [PubMed]

16. Jeswani S, Nuño M, Folkerts V, Mukherjee D, Black KL, Patil CG. Comparison of survival between cerebellar and supratentorial glioblastoma patients: Surveillance,  Epidemiology, and End Results (SEER) analysis. Neurosurgery 2013;73:240-246. [PubMed]

17. Dohrmann GJ, Dunsmore RH. Glioblastoma multiforme of the cerebellum. Surg Neurol 1975;3:21 9-223.

18. Kuroiwa T, Numaguchi Y, Rothman MI, et al. Posterior Fossa Glioblastoma Multiforme: MR Findings. AJNR Am J Neuroradiol 1995;16:583-589. [PubMed]

19. Levine SA, McKeever PE, Greenberg HS. Primary cerebellar glioblastoma multiforme. J Neurooncol 1987;5:231-236. [PubMed]

20. Djalilian HR, Hall WA. Malignant gliomas of the cerebellum: an analytic review. J Neurooncol 1998;36:247-257. [PubMed]

21. Kast RE. Why cerebellar glioblastoma is rare and how that indicates adjunctive use of the FDA-approved antiemetic aprep-itant might retard cerebral glioblastoma growth: a new hypothesis to an old question. Clin Transl Onc ol 2009;11:408-410.

22. Mattos JP, Marenco HA, Campos JM, et al. Cerebellar glioblastoma multiforme in an adult. Arq Neuro-psiquiatr 2006;64(1):132-135. [Abstract/Full-Text]

23. Hamilton MG, Tranmer BI, Hagen NA. Supratentorial glioblastoma with spinal cord intramedullary metastasis. Can J Neurol Sci 2003;20:65-8. [Abstract/Full-Text]

24. Vertosick Jr FT, Selker RG. Brain stem and spinal metastases of supratentorial glioblastoma multiforme: a clinical series. Neurosurgery 1990;27:516-21. [PubMed]

25. Wisoff HS, Llena JF. Glioblastoma multiforme of the cerebellum five decades after irradiation of a cerebellar tumor. J Neurooncol 1989;7:339-344. [PubMed]

26. Schmidbauer M, Budka H, Bruck-ner R, Vorkapic P. Glioblastoma developing at the site of a cerebellar medulloblastoma treated 6 years earlier: case report. J Neurosurg 1987;67:915-918. [Abstract/Full-Text]

27. Ushio Y, Arita N, Yoshimine T, Ikeda T, Mogami H. Malignant recurrence of childhood cerebellar astrocytoma: case report. Neuro-surgery 1987;21:251-255. [PubMed]

28. Maat-Schieman ML, Bots GT, Tho-meer RT, Vielvoye GJ. Malignant astrocytoma following radiotherapy for craniopharyngioma. Br J Radiol 1985;58:480-482. [Abstract/Full-Text]

29.Hur H, Jung S, Jung TY, Kim IY.  Cerebellar Glioblastoma Multiforme in an Adult. J Korean Neuro-surg Soc 2008;43:194-197. [Abstract/Full-Text]

30. Kawarabuki K, Ohta T, Hashimoto N et al. Cerebellar glioblastoma genetically defined as a secondary one. Clin Neuropathol 2005;24:64-68. [PubMed]

31. Saito T, Hama S, Kajiwara Y et al. Prognosis of cerebellar glioblastomas: correlation between prognosis and immunoreactivity for epidermal growth factor receptor compared with supratentorial glioblastomas. Anticancer Res 2006;26:1351-1357. [PubMed]

32. Capper D, Weissert S, Balss J et al. Characterization of R132H muta-tion specific IDH1 antibody binding in brain tumors. Brain Pathol 2010;20:245-254. [PubMed]

33. Watanabe K, Tachibana O, Sata K et al. Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 1996; 6:217-224. [PubMed]

34. Weber DC, Miller RC, Villa S, et al. Outcome and prognostic factors in cerebellar glioblastoma multiforme in adults: a retrospective study from the rare cancer network. Int J Radiat Oncol Biol Phys 2006;66: 179-186. [PubMed]

35. Akimoto J, Fukami S, Tsutsumi M et al. Radiopathological characteristics of cerebellar malignant glioma in adults. Brain Tumor Pathol 2009;26:59-68. [Abstract/Full-Text]

36. Barker FG, Simmons ML, Chang S, et al. EGFR overexpression and radiation response in glioblastoma multiforme. Int J Radiat Oncol Biol Phys 2001;51:410-418. [PubMed]

37. Pang D, Ashmead JW. Extraneural metastasis of cerebellar glioblastoma multiforme. Neurosurgery 1982;10(2):252-257. [PubMed]

38. El Maaqili MR, Hossini A, El Fatemi N, et al. Primary glioblastoma of the cerebellum in a 19-year-old- woman: a case report. Journal of Medical Case Reports 2012;6: 329. [Abstract/Full-Text]

39. Zito JL, Siva A, Smith TW, Leeds M, Davidson R. Glioblastoma of the cerebellum. Computed tomographic and pathologic considerations. Surg Neurol 1983;19:373-378. [PubMed]

40. Law M, Cha S, Knopp EA, Johnson G, Arnett J, Litt AW. High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR Imaging. Radiology 2002;222:715-721. [PubMed]

41. Chaichana K, Parker S, Olivi A, Quiñones-Hinojosa A. A proposed classification system that projects outcomes based on preoperative variables for adult patients with glioblastoma multiforme. J Neurosurg 2010;112:997-1004. [Abstract/Full-Text]

42. Laws ER, Parney IF, Huang W, et al. Glioma outcomes investigators: survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project. J Neurosurg 2003;99:467-473.

43. Bi WL, Chiocca EA. Adult Cerebellar Glioblastomas: A Distinct entity or parcel of the whole? World Neurosurg 2013;80,6:e181-e183. [Abstract/Full-Text]

44. Stupp R, Mason WP, van den Bent MJ, et al. European organization for research and treatment of cancer brain tumor and radiotherapy groups; national cancer institute of Canada Clinical Trials Group: radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987-996.

45. Grossman SA, Ye X, Piantadosi S, Desideri S et al. NABTT CNS Consortium. Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States. Clin Cancer Res 2010;16:2443-2449. [Abstract/Full-Text]

46. Kaur G, Bloch O, Jian BJ, et al. A critical evaluation of cystic features in primary glioblastoma as a prognostic factor for survival. J Neur-osurg 2011;115:754-759. [Abstract/Full-Text]

47. Yang S, Liu J, Wang T, Li X, You C. Cerebellar glioblastoma multi-forme: a retrospective study of 28 patients at a single institution. International Joumal of Neuroscience 2013;123(10):691-697. [PubMed]

48. Giese A, Bjerkvig R, Berens ME, Westphal M. Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol 2003;21:1624-1636. [PubMed]

READ THE FULL ARTICLE

limited access

1. Access this article  through your login credentials or your institution

Get Access

2. Access this article through OpenAthens/Sign in

3. Purchase this article at rate $55.00 and received Full-Text/PDF
You will have online immediate access to article following the completion of this purchase and you may download and print a copy of each article for your personal use. Use the coding below to purchase your article as PDF by credit card, debit card, payball will be asked to supply your billing card information. Before continue with your purchase please read carefully the AJBM terms and conditions of purchase.

Purchase Article

 For any technique error please contact us and will be response to sending purchase article by email.

Thank you for visiting American Journal of BioMedicine.  * = Required fields

[gravityform id=”6″ name=”Feedback”]

American Journal of Biomedicine © 2017 Frontier Theme
%d bloggers like this: