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Chronic fatigue syndrome in patient with ALK-positive anaplastic large cell lymphoma

 
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Research Article 
dx.doi.org/10.18081/2333-5106/016-4/75-80
American Journal of BioMedicine Volume 4, Issue 4, pages 75-80
Received December 19, 2015; accepted March 08, 2016; published April 10, 2016

Stephen B. Larsena, Christian M. Junghanssa, Angela, Bo Hye Kimb, Patrick B. Schnellamail of corresponding author

Abstract

Anaplastic large cell lymphoma (ALCL) is a rare type of NHL, and more common subtypes of T-cell lymphoma, we report a case of ALK-positive anaplastic large cell lymphoma preceded by long history of chronic fatigue syndrome. A 75-year-old patient recently developed cervical lymphadenopathy, pyrexia, weight loss, night sweats. Chest computed tomography scan showed widening of the superior mediastinum. Magnetic resonance imaging of the spine demonstrated spinal effacement at T7 raising the risk of cord compression. A lymph node biopsy showed positive anaplastic large cell lymphoma. Patient was treated with standard first-line chemotherapy proceed to the autologous stem cell transplantation.

Keywords: ALK; NHL; Cervical Lymphadenopathy

Copyright © 2016 by The American Society for BioMedicine and BM-Publisher, Inc.

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