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Study the association of visfatin in the pathogenesis of meconium stained amniotic fluid in labour

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doi: 10.18081/ajbm/2333-5106/015-04/181-187
American Journal of BioMedicine Volume 3, Issue 4, pages 181-187
Published: April 23, 2015


Basima Sh. Alghazali

Abstract  

Meconium staining of the amniotic fluid and the meconium aspiration syndrome (MAS will likely remain common occurrences faced by health care providers. Unfortunately, our understanding of these entities is incomplete. There are a number of issues which need to be adequately evaluated regarding the pathophysiology of MAS. The objectives of this study is to investigate the association of visfatin in the pathogenesis of meconium stain amniotic fluid. A case control study, conducted in Al-Zahra teaching hospital/ALNajaf city where 90 women delivered studied, 45 with meconium stained amniotic fluid (MSAF) and 45 clear amniotic fluid (CAF) where study from first of March 2013 to July 2013 in the labour room and operative theater, data collected regarding their names, gestational age, sex, type of the meconium, mode of delivery, outcome and parity of the mother. Aspiration of blood done and the concentration of visfatin in amniotic fluid were determined using a specific and sensitive enzyme immunoassay. We concluded that, the level of visfatin is increased significantly in MSAF in comparison with the CAF group.

Keywords: Visfatin; Meconium aspiration syndrome; Amniotic fluid; Labour


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