This study aims to determine the effect of Fertilaid and L- carnitine on the oxidative stress and seminal fluid parameters of the infertile male. One hundred male participants were involved in this study. Seminal fluid samples were collected in duplicates and they were exposed into two forms of in vitro treatments: Fertilaid, and traditional L carnitine. The in vitro sperm stimulation by L Carnitine and Fertilaid in nutrient mixture Ham's F-10 have a significant increase in the activity of the motile sperm (sperm/million) (30.99 for grade A; 30.25 for grade B and 29.68 for grade C) as compared to sperm activation using L carnitine (sperm/million) (27.03 for grade A; 27.40 for grade B and 22.16 for grade C), p<0.05. Seminal levels of Malondialdehyde (1.02 nmol/ml) was significantly elevated in the infertile samples as compared to the fertile samples (0.94 nmol/ml), P<0.05. This was associated with a significant reduction in the seminal levels of reduced glutathione in the infertile samples (5.67 nmol/ml) as compared to the fertile samples (7.10 nmol/ml), p<0.01. In conclusion, in vitro semen activation by fertilaid showed a significant increase in the overall semen parameters as compared to the activation by L. Carnitine.
Keywords: Fertilaid; Hams-F10; L Carnitine; Malondialdehyde; Glutathione; Male infertility
Copyright © 2019 by The American Society for BioMedicine and BM-Publisher, Inc.
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American Journal of BioMedicine Volume 8, Issue 2, pages 65-72
Received October 11, 2019; accepted February 02, 2020; published February 23, 2020
How to cite this article
Hamashareef SR, Alwasiti1 EA, Tahseen YH, Hussein MM, Al-Aubaidy HA. A new stimulatory method for activation of sperm functions using Fertilaid in male infertility. American Journal of BioMedicine 2020;8(2):/65-72.
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