Abstract
The pathogenesis of migraine is still unknown, the hemodynamics and vascular hypothesis had been tested by many investigators using different methods including angiography, isotopes scan, PET and SPECT scans. In this study, we are assessing the use of TCD to determine cerebral blood flow and vasoreactivity response by using breath-holding test among Iraqi migraine patients. Study group included a total of 57 patients diagnosed with migraine; 42 female patients and 15 male patients, they ranged in age from 15 to 37 years. Migraine of twenty patients were accompanied with aura and thirty-seven patients had no aura. We found no significant difference in peak systolic velocity, diastolic velocity, resistive index, and pulsatility index between the study and the control groups and between the patients with and without aura. Using breath holding index, we found a significant difference between the study and the control group but no significant difference between patients with and without aura and no difference in gender. For the best of our knowledge, this is the first study that supports the role of neurovascular changes via assessment of cerebral blood flow and breath hold vasoreactivity using TCD testing.
Keywords: Transcranial doppler ultrasound; Cerebral blood flow; Breath-holding vasoreactivity
Copyright © 2020 by Rhadi M., et al.
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Research Article
DOI: http://dx.doi.org/10.18081/2333-5106/018-10/648-660
American Journal of BioMedicine Volume 8, Issue 3, pages 165-177
Received March 30, 2020; Accepted July 11, 2020; Published August 14, 2020