Cheng Chen, Guo-Wei Feng, Hui Zeng, Shiheng Zhang 1
Abstract
The objective is chemical analysis instruments and the changes in nephrolithiasis characteristics over decades. Information from a longitudinal data set could help reveal factors associated with a high incidence of nephrolithiasis. Cohort study, based on data from the Instrument for Personalized Antibiotic Therapy and Surgery, held at Fujian Provincial Hospital between 1972 and 2013. Sixteen thousand, seven hundred and three individuals with urinary stone disease were recruited to assess demographic, body mass index, and body surface area data. Twenty-seven thousand, five hundred eighty nonstone forming individuals with complete blood count and serum tests were involved in a supplementary analysis. The overall incidence was observed to be 52.35% in males and 8.26% in females, with urate stones representing the bulk of the stones (males: 43.67%; females: 18.89%). Age, gender, and body mass index were associated with stone formation after backward LR analyses. Increasing age and body mass index were incrementally associated with higher odds of nephrolithiasis. Decreases in platelet count and red cell distribution width were associated with increasing gender-specific incidence of stone components (white cell count could not be involved in the equation), but the range of platelet count and the increase in red cell distribution width were different between uric acid stone and calcium stones.
Keywords: Prevalence, Nephrolithiasis, China
Copyright © 2018 by The American Society for BioMedicine and BM-Publisher, Inc.
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