Hassan Abdulla Abadi AL- Aqulia 
Abstract
Echinococcosis is an endemic zoonotic disease caused by the dog tape-worm Echinococcus granulosus. Surgical treatment and percutaneous drainage have been used for the treatment of hydatid cysts. However, inactivation of the parasite with protoscolicidal agents is a crucial part in the treatment in both methods. The aim of this study was to evaluate the protoscolicidal effect of cetrimide and povidone-iodine in hydatid cyst disease. Fifty intact cysts of pulmonary hydatid disease of patients not received preoperative antihelmenthic were included in the study. While those cysts of patients who received preoperative antihelmenthic were excluded from the study. The protoscolicidal effect of cetrimide (0.05%, 0.1%, 0.5%) and povidone-iodine (10%) were assessed in this in vitro study using 1, 2 and 5 minutes as exposure time. Cetrimide (0.1%, 0.5%) have a higher protoscolicidal effect than 10% povidone-iodine that is statistically significant after different exposure time. The data concluded that cetrimide (0.1%) is a very effective protoscolicidal agent even with short exposure time, so it is the least concentration dependent and the least time dependent to achieve its protoscolicidal effect.
Keywords: Hydatid cyst; Viability; Protoscolicidal agents
Copyright © 2016 by The American Society for BioMedicine and BM-Publisher, Inc.
1. Atalay F, Kirimlioglu V, Gundogdu H, Akincioglu T, Gencer A. Surgery for hydatid cysts of the liver. Hiroshima J Med Sci 1995;44: 89-92. [PubMed]
2. Seymour I. Schwartz and Harold Ellis. Maingot s Abdominal Operations, 9th edition, Vol. II, Appleton and Lange 1997. Section XI (51) the liver 1535-1545.
3. Rodenck N M Macsween, Keith Whaley: Muirs Textbook of pathology,13th edition,1992;1174-1176.
4. Akyildiz HY, Akcan A, Karahan I, et al. Recurrent liver hydatid disease: when does it become symptomatic and how does one diagnose it? Clin Imaging 2009;33:55-8. [PubMed]
5. Akhan O, Özmen MN. Percutaneous treatment of liver hydatid cyst. Eur J Radiol 1999;32:76-85. [PubMed]
6. Canyigit M, Gumus M, Cay N, et al. Refractory cystobiliary fistula secondary to percutaneous treatment of hydatid cyst: treatment with N-butyl 2-cyanoacrylate embolization. Cardiovasc Intervent Radiol 2011;34(Suppl. 2):266-70. [PubMed]
7. Karayalçin K, Besim H, Sonisik M, Erverdi N, Korkmaz A, Aras N. Effect of hypertonic saline and alcohol on viability of daughter cysts in hepatic hydatid disease. Eur J Surg 1999;165:1043-4. [ PubMed]
8. Symith JD, Barret NJ. Procedures for testing the viability of human hydatid cyst following surgical removal, especially after chemotherapy. Tran R Soc Trop Med and Hyg 1980;74(5):649-652. [PubMed]
9. Morris DL, Chinnery JB, Ubhi C. A comparison of the effect of albendazole, its sulphone metabolite, and mebendazole on the viability of protoscolices of E. granulosus in an in vitro culture system. Trans R Soc Trop Med Hyg 1987;81:804-806. [PubMed]
10. Pawlowski ZS, Eckert J, Vuitton DA, et al. Echinococcosis in human and clinical aspects, diagnosis and treatment. In Manual on Echinococcosis in human and animal. A Public Health Problem of Global Concern 2001;20-71.
11. Frayha GJ, Bikhazi KJ, Kachachi TA. Treatment of hydatid cysts (Echinococcosis granulosus) by Cetrimide (R). Trans R Soc Trop Med Hyg 1981;75(3):447-450. [PubMed]
12. Besim H, Karayalcin K, Hamaci O, Gungor C, Korkmaz A. Scolicidal agents in hydatid cyst surgery. HPB Surg 1998;10(6):347-351. [PubMed]
13. Ahrari H. Use of Cetremide in the surgery of hydatid cyst. Bull Soc Pathol Exot Filiales 1978;71(1):90-94. [PubMed]
14. Hosseini SV, Ghanbarzadeh K, Barzin J, et al. In vitro protoscolicidal effects of hypertonic glucose on protoscolices of hydatid cyst. Korean Journal of Parasitology 2001; 44:239-242. [PubMed]
15. Castellano G, Moreno-Sanchez D, et al. Caustic sclerosing cholangitis. Report of four cases and accumulative review of the literature. Hepatogastroenterology 1994;41:458-470. [PubMed]
READ THE FULL ARTICLE
1. Access this article through your login credentials or your institution
2. Purchase this article at rate $55.00 and received Full-Text/PDF
For any technique error please contact us and will be response to sending purchase article by email.
Thank you for visiting American Journal of BioMedicine. * = Required fields
[gravityform id=”6″ name=”Feedback”]
References
You will have online immediate access to article following the completion of this purchase and you may download and print a copy of each article for your personal use. Use the coding below to purchase your article as PDF by credit card, debit card, payball will be asked to supply your billing card information. Before continue with your purchase please read carefully the AJBM terms and conditions of purchase.
