Prevalence of hepatitis C virus infection among hemodialysis patients: cohort study




Research Article

American Journal of BioMedicine
Volume 11, Issue 1, 23 February 2023, Pages 36-44 | http://dx.doi.org/10.18081/2333-5106/2023.11/36

Dimie Aruna 1, Abubakar Adereti 1, 2, Easley A. Munir 1*  

Author Affiliations
*Correspondence author e-mail: Easley_Munir22 @gmail.com: 1 Epidemiology Training program, Abuja, Nigeria. 2 Department of Immunization, World Health Organization, Geneva, Switzerland.

Received  12 August  2022   Revised  30 November 2022   Accepted  11 January 2023   Published  23 February 2023

 

Abstract

Hepatitis C virus (HCV) is a blood-borne virus that primarily infects the liver and can cause both acute and chronic hepatitis. HCV is one of the leading causes of liver disease worldwide and can lead to cirrhosis, liver failure, and liver cancer if left untreated. Dialysis is the most common reliable and accessible therapeutic approach in end-stage renal disease (ESRD) which increases survival and life expectancy in patients. Despite the screening tests on blood products and devices, nosocomial infections are one of leading causes of morbidity and mortality in ESRD. HCV is more prevalent in ESRD compared to the general population, with an overall prevalence of 9.9% among chronic hemodialysis (CHD) patients in high- and middle-income countries. The objective of this study is to assess the prevalence of occult HCV infection in CHD. All clinical, and demographic data was registered beside blood samples, serological testes and HCV-RNAs from 95 patients; 60.7% were male, with mean age of OCI positive cases was 32.3 ± 14.3 years. Furthermore, three case had detectable viral load which was 54 IU/ml. Inconclusion, there is a risk of OCI among CHD patients that needs follow-up by molecular testing.

Keywords: Hepatitis C virus (HCV); End-stage renal disease; HCV-RNAs

Copyright © 2023 Easley A. Munir, et al. This article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Aruna D, Adereti A, Munir EA. Prevalence of hepatitis C virus infection among hemodialysis patients: cohort study. American Journal of BioMedicine 2023; 11(1):36-44.

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APA
Aruna, D., Adereti, A., & Munir, E. A. (2023). Prevalence of hepatitis C virus infection among hemodialysis patients: cohort study. American Journal of Biomedicine, 11(1), 36–44. doi:10.18081/2333-5106/2023.11/36
MLA
Aruna, Dimie, et al. “Prevalence of Hepatitis C Virus Infection among Hemodialysis Patients: Cohort Study.” American Journal of Biomedicine, vol. 11, no. 1, 2023, pp. 36–44, doi:10.18081/2333-5106/2023.11/36.
HARVARD
Aruna, D., Adereti, A. and Munir, E. A. (2023) “Prevalence of hepatitis C virus infection among hemodialysis patients: cohort study,” American journal of biomedicine, 11(1), pp. 36–44. doi: 10.18081/2333-5106/2023.11/36.
VANCOUVER
Aruna D, Adereti A, Munir EA. Prevalence of hepatitis C virus infection among hemodialysis patients: cohort study. Am J Biomed [Internet]. 2023;11(1):36–44. Available from: http://dx.doi.org/10.18081/2333-5106/2023.11/36

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