Transcranial doppler findings in basilar artery dolichoectasia: a case control study

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American Journal of BioMedicine Volume 9, Issue 4, pages 208-219

Zaid Ali Hussein1, Haider N. Al-Tameemi*2, Hayder Kadhum Hassoun2, Ahmed MH Almudhafar2

Author Affiliations
∗Correspondence author e-mail: haidern.altameemi@uokufa.edu.iq: 1Middle Euphrates Neuroscience Center, Al-Najaf health directorate, 2Middle Euphrates Neuroscience Center and Faculty of Medicine/ University of Kufa.

 

Abstract

Basilar artery dolichoectasia (BAD) is a disorder characterized by dilatation, elongation and tortuosity of the basilar artery. Transcranial Doppler ultrasound (TCD) is a useful tool that can detect blood flow in intracranial vessels including basilar artery (BA). Few studies have been conducted on blood flow changes in BAD. This study was conducted to evaluate the Doppler parameters in dolichoectatic BA and to assess if there is any difference in TCD findings between stroke and non-stroke BAD patients.  A case-control study was conducted on 35 patients diagnosed with BAD (26 male, 9 female) and 35 age- and gender-matched control group (without BAD) at the Middle Euphrates Neuroscience Center, Al-Sader Medical City, Al-Najaf, Iraq. Dolichoectasia was diagnosed on non-enhanced brain CT scan using established imaging criteria according to Dan Deng et al criteria. Doppler flow for control and stroke cases was recorded. The parameters measured on TCD were peak systolic velocity (PSV), end diastolic velocity (EDV) mean blood velocity (MBV), pulsatility index (PI) and resistive index (RI). After logistic regression for adjustment for the significant confounders, there was statistically significant difference in Doppler parameters between both groups including decrease in each of PSV, EDV and MBV while both PI and RI weren’t statistically significant. Among BAD patients, there was statistically significant difference in all TCD parameters between stroke and non-stroke patients (PSV EDV, MBV, PI and RI). BAD was associated with a decrease in flow velocities as measured by TCD. Furthermore, among BAD patients, those with stroke had lower values for all Doppler parameters than non-stroke patients.

Keywords: Basilar artery, Dolichoectasia, Transcranial Doppler, stroke, Computed tomography

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Transcranial doppler findings in basilar artery dolichoectasia a case control study

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    Research Article
    http://dx.doi.org/10.18081/2333-5106/9.4/188
    American Journal of BioMedicine Volume 9, Issue 4, pages 208-219
    Received October 10, 2021; revised November 25, 2021; accepted December 05, 2021; published December 14, 2021

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    How to cite this article
    Hussein ZA,Al-Tameemi HN, Hassoun HK, Almudhafar AM. Transcranial doppler findings in basilar artery dolichoectasia: a case control study. American Journal of BioMedicine 2021;9(4):208-219.
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