Volume 10, Issue 2, April 30 2022, Pages 49-60
Jessica A Braden, Erin M Peairs, Jaya H Onitilo, Michael K Temkit 1*
Abstract
Prognosis in patients with breast cancer depends mainly on the extent of lymph node involvement, size of the tumor, and the histological grade of the tumor. Among these factors, axillary lymph node status is regarded as the single best marker of prognosis. Sentinel lymph node biopsy has become a standard staging tool in the surgical management of breast cancer. The positive impact of sentinel lymph node biopsy on postoperative negative outcomes in breast cancer patients, without compromising the oncological outcomes, is its major advantage. It has evolved over the last few decades and has proven its utility beyond early breast cancer. Its applicability and efficacy in patients with clinically positive axilla who have had a complete clinical response after neoadjuvant chemotherapy is being aggressively evaluated at present. However, the accuracy of sentinel lymph node biopsy after neoadjuvant chemotherapy in patients with metastatic breast cancer is unclear. This review study discusses role of sentinel lymph node biopsy in role in advance breast cancer a useful tool in new clinical scenarios of metastatic breast cancer management.
Keywords: Sentinel lymph node biopsy; Metastatic breast cancer; Neoadjuvant chemotherapy
Copyright © 2021 Temkit MK et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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