Chronic fatigue syndrome in patient with ALK-positive anaplastic large cell lymphoma

Research Article
American Journal of BioMedicine Volume 8, Issue 1, pages 13-20
Received November 30, 2019; Accepted December 15, 2019; Published January 11, 2020

Stephen B. Larsen 1, Christian M. Junghanss 1, Angela, Bo Hye Kim 2, Patrick B. Schnell 1


Anaplastic large cell lymphoma (ALCL) is a rare type of NHL, and more common subtypes of T-cell lymphoma, we report a case of ALK-positive anaplastic large cell lymphoma preceded by long history of chronic fatigue syndrome. A 75-year-old patient recently developed cervical lymphadenopathy, pyrexia, weight loss, night sweats. Chest computed tomography scan showed widening of the superior mediastinum. Magnetic resonance imaging of the spine demonstrated spinal effacement at T7 raising the risk of cord compression. A lymph node biopsy showed positive anaplastic large cell lymphoma. Patient was treated with standard first-line chemotherapy proceed to the autologous stem cell transplantation.

Keywords: ALK; NHL; Cervical Lymphadenopathy

Copyright © 2020 by Schnell et al. This article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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