Advertisement

Estimated glomerular filtration rate from serum creatinine in Brazil/changing in CKD

 
crossMark

doi: 10.18081/2333-5106/015-06/325-332
American Journal of BioMedicine Volume 3, Issue 6, pages 325-332
Published: June 22, 2015


Continued progression of kidney disease will lead to renal function too low to sustain healthy life. In developed countries, such people will be offered renal replacement therapy in the form of dialysis or renal transplantation. Estimates of glomerular filtration rate (GFR) that are based on serum creatinine are routinely used; however, they are imprecise, potentially leading to the overdiagnosis of chronic kidney disease. The purpose of this study is to evaluate the glomerular filtration rate from serum creatinine in Brazil patients with chronic kidney disease (CKD). Multiple equations exist to estimate glomerular filtration rate (GFR); however, there is no consensus on which is superior for risk classification in patients with chronic kidney disease (CKD). Renal function was analyzed through serum creatinine and glomerular filtration rate (GFR) estimated according to the CG, MDRD and CKD-EPI equations, available on the websites of the Brazilian Nephrology Society (SBN) and the (NKF) by using cross-sectional analyses in diverse populations totaling 3949 participants.

Keywords: Chronic kidney disease (CKD); Glomerular filtration rate (GFR);Renal function; Serum creatinine
 

Limited Access              Full Text-PDF                   Cited-by-Linkin


References

1. Stevens LA, Padala S, Levey AS. Advances in glomerular filtration rate-estimating equations. Curr Opin Nephrol Hypertens 2010;19:298-307. [PubMed]

2. Levey AS, Eckardt KU, Tsukamoto Y, et al. Definition and classification of chronic kidney disease: A position statement from Kidney Disease. Improving Global Outcomes (KDIGO) Kidney Int 2005;67(6):2089–100. [PubMed]

3. Sarnak MJ, Levey AS, Schoolwerth AC, et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Hypertension 2003;42(5):1050–65. [PubMed]

4. Coresh J, Astor B, Sarnak M. Evidence for increased cardiovascular disease risk in patients with chronic kidney disease. Curr Opin Nephrol Hypertens 2004;13(1):73–81. [PubMed]

5. Kwong YT, Stevens LA, Selvin E, et al. Imprecision of urinary iothalamate clearance as a gold-standard measure of GFR decreases the diagnostic accuracy of kidney function estimating equations. Am J Kidney Dis 2010;56:39-49. [PubMed]

6. Stevens LA, Coresh J, Greene T, Levey AS. Assessing kidney function — measured and estimated glomerular filtration rate. N Engl J Med 2006;354:2473-2483. [PubMed]

7. Myers GL, Miller WG, Coresh J, et al. Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program. Clin Chem 2006;52(1):5–18. [PubMed]

8. Mathew TH. Chronic kidney disease and automatic reporting of estimated glomerular filtration rate: a position statement. Med J Aust 2005;183(3):138–41. [PubMed]

9. Coresh J, Stevens LA, Levey AS. Chronic kidney disease is common: what do we do next?Nephrol Dial Transplant 2008;23(4):1122–5. [PubMed]

10. Eckardt KU, Berns JS, Rocco MV, et al. Definition and classification of CKD: the debate should be about patient prognosis–a position statement from KDOQI and KDIGO. Am J Kidney Dis 2009;53(6):915–20. [PubMed]

11. Fontsere N, Bonal J, Salinas I, et al. Is the new Mayo Clinic Quadratic equation useful for the estimation of glomerular filtration rate in type 2 diabetic patients? Diabetes Care  2008;31(12):2265–7. [PubMed]

12. Grubb A, Nyman U, Bjork J, et al. Simple cystatin C-based prediction equations for glomerular filtration rate compared with the modification of diet in renal disease prediction equation for adults and the Schwartz and the Counahan-Barratt prediction equations for children. Clin Chem 2005;51(8):1420–31. [PubMed]

13. Larsson A, Malm J, Grubb A, et al. Calculation of glomerular filtration rate expressed in mL/min from plasma cystatin C values in mg/min. Scand J Clin Lab Invest 2004;64(1):25–30. [PubMed]

14. Coresh J. CKD prognosis: beyond the traditional outcomes. Am J Kidney Dis. 2009;54(1):1–3. [PubMed]

15. Stevens LA, Levey AS. Use of the MDRD study equation to estimate kidney function for drug dosing. Clin Pharmacol Ther. 2009;86(5):465–7. [PubMed]

16. Melloni C, Peterson ED, Chen AY, et al. Cockcroft-Gault versus modification of diet in renal disease: importance of glomerular filtration rate formula for classification of chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes. J Am Coll Cardiol 2008;51(10):991–6. [PubMed]

17. Wargo KA, Eiland EH, 3rd, Hamm W, et al. Comparison of the modification of diet in renal disease and Cockcroft-Gault equations for antimicrobial dosage adjustments. Ann Pharmacother 2006;40(7–8):1248–53. [PubMed]

18. Food and Drug Administration. Guidance for Industry: Pharmacokinetics in Patients with Impaired Renal Function Study Design, Data Analysis, and Impact on Dosing and Labeling. U.S. Department of Health and Human Services; Rockville:1998.

19. Stevens LA, Levey AS. Impact of reporting estimated glomerular filtration rate: it's not just about us. Kidney Int 2009;76(3):245–7. [PubMed]

20. Xie D, Joffe M, Brunelli S, et al. A comparison of change in measured and estimated glomerular filtration rate in patients with nondiabetic kidney disease. Clin J Am Soc Nephrol 2008;3:1332–1338. [PubMed]

21. Grubb A, Bjork J, Lindstrom V, et al. A cystatin C-based formula without anthropometric variables estimates glomerular filtration rate better than creatinine clearance using the Cockcroft-Gault formula. Scand J Clin Lab Invest 2005; 65(2):153–62. [PubMed]

22. Knight EL, Verhave JC, Spiegelman D, et al. Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney Int 2004;65(4):1416–21. [PubMed]

 

American Journal of Biomedicine © 2017 Frontier Theme
%d bloggers like this: