Abstract
Infertility is a common medical and social concern. Azoospermia is a syndrome with different histopathological changes, hormonal disturbances and altered size of testes. The aim of this work is to assess testicular histopathogical patterns, measure the volume of testis and the size of the seminiferous tubules in the spectrum of the azoospermic patients along with examining hormonal changes. Seventy-eight (78) azoospermic cases were included in this study within the reproductive age group (18-50) years old. Proper history was taken through a detailed questionnaire; physical examination was performed. Testicular volume was calculated using ultrasonography and Lamberts’ formula (L (length) x W (width) x H (height) x 0.71). The level of LH, FSH and Testosterone hormones was determined. The mean testicular volume (mL) in obstructive azoospermia (OA) was (16.90), in M.A was (15.17), in SCOS was (9.13), in HS was (13.1) and in end-stage was (7.59). The mean diameter of seminiferous tubules (micron), in OA was (171.55), in M.A was (154.53), in SCOS was (121.55), in HS was (165.47) and in end-stage was (116.92). The hormonal profile of FSH (mIu/ml) in OA was (5.33), in M.A was (8.22), in SCOS was (22.59), in HS was (6.74), and in end-stage was (25.4). The level of LH (mIu/ml) in OA was (5.78), MA; (7.1), SCOS; (14.44), HS; (5.57), and end-stage (13.12) while the hormonal profile of testosterone (ng/ml) in OA was (5.64), M.A; (5.19), SCOS; (3.57), HS; (4.91) and end stage (2.08). In conclusion; non obstructive pathologies are still the commonest causes of azoospermia that are associated with variable level of size change and disturbance in hormonal level. Histopathology is the corner stone for proper diagnosis.
Keywords: Azoospermia; Testes; Seminiferous tubules
Copyright © 2019 by The American Society for BioMedicine and BM-Publisher, Inc.
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