“Topic Review”
Month: December 2015
Over expression of IL-32 in rheumatoid arthritis modulates NF-κB activity
Research Article dx.doi.org/10.18081/2333-5106/015-12/793-811 American Journal of BioMedicine Volume 3, Issue 12, pages 793-811Received: April 02, 2015; accepted: November 22, 2015; published: December 25, 2015 Sergio Ayalaa, Peter G. Thurya, Rui Chena, b, Jone A. Fishbeina, Maria Wisemana, Florian K. Dinulescua Abstract IL-32 is pro-inflammatory cytokine characterized by the induction of nuclear factor NF-κB […]
Critical role of EP2-PKA signaling reduced myocardial function via macrophages activation
Research Article dx.doi.org/10.18081/2333-5106/015-12/780-792 American Journal of BioMedicine Volume 3, Issue 12, pages 780-792 Received: July 23, 2015; accepted: October 30, 2015; published: December 19, 2015 Carmen S. Bootha, Hashimoto G. Weisa, b, Pablo Halesa, Amanda H. Matherlya, Lynn C. Grafa Abstract Upon tissue damage or infection, monocytes are rapidly recruited to the tissue, where they […]
TAK-242 attenuates renal ischemia and reperfusion injury by inhibiting TLR4 signaling pathway
Research Article dx.doi.org/10.18081/2333-5106/015-12/769-779 American Journal of BioMedicine Volume 3, Issue 12, pages 769-779 Received: July 30, 2015; accepted: October 28, 2015; published: December 12, 2015 Tamas Wilsona, Stefan A. Wieland, Mark Matsunagaa, ShuJun Zhanga, b Abstract TAK-242 (resatorvid), a small-molecule–specific inhibitor of Toll-like receptor (TLR) 4 signaling, has been demonstrated to protect renal […]