Abnormal thyroid function and risk factor of gestational diabetes mellitus: a systematic review and meta-analysis

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El Houssaine Mansour, Omar Bouamra ¹*


The prevalence of gestational diabetes mellitus is reported to be increasing in last recent years. Pregnant women become progressively more insulin resistant due to multi factors like release of placental hormones. The present study investigate the incidence of gestational diabetes mellitus concomitant with abnormal thyroid function in a cohort of 4178 Morocco women. We used Cox-model to investigate the association of thyroid function test with gestational diabetes and explore effects of other risk factors, including gynecological disorders and birth weight of offspring. This study concluded that low thyroid function are risk factors for incident gestational diabetes and more studies needs to investigate the subclinical cases of hypothyroidism.

Keywords: Diabetes mellitus; Gestation; Pregnant women

Copyright © 2016 by The American Society for BioMedicine and BM-Publisher, Inc.

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DOI: http://dx.doi.org/10.18081/2333-5106/017-2/86-98
American Journal of BioMedicine Volume 5, Issue 2, pages 86-98
Received October 04, 2016; accepted January 05, 2017; published February 09, 2017

How to cite this article
El Houssaine M, Bouamra O. Abnormal thyroid function and risk factor of gestational diabetes mellitus: a systematic review and meta-analysis. American Journal of BioMedicine 2017;5(2):86-98.

Article outline
1. Abstract
2. Keywords
3. Introduction
4. Methods
5. Results
6. Discussion
7. Acknowledgements
8. References