Role of continuous renal replacement therapy (CRRT) in septic acute kidney injury patients

Research Article
American Journal of BioMedicine Volume 4, Issue 6, pages 219-226
Received January 21, 2016; accepted May19, 2016; published June 12, 2016

Iyad Abbas Salman1, Waleed Ibraheem Ali1, Mohammed Younus Naji Al Atbee2, Mohanad Abdulkareem Hilal3mail of corresponding author


The systemic inflammatory response syndrome (SIRS) and sepsis are complex syndromes resulting from an inciting insult that causes systemic inflammation, leading to widespread tissue injury mainly acute kidney injury AKI. It's an overwhelming inflammatory and coagulopathic response to a source of infection, usually from the lung or abdomen. If not recognized early, or not treated properly and aggressively, it is often a lethal outcome. The objectives of this study is to determine the therapeutic efficacy and safety of continuous renal replacement therapy (CRRT) in the treatment of Patients with septic AKI. This is cross sectional study were 43 patients with sepsis and acute kidney injury included and  they were undergo management by using  (CRRT plus conventional therapy ) in intensive care unit (ICU) of Ghazi Al Hariri teaching hospital in a period from August 2014 to April 2015. Our study showed that 23 out of 43 patients with septic AKI who were treated by continuous renal replacement therapy CRRT were improved and 20 patients were not get benefit of treatment (died). In conclusions, CRRT is an important adjuvant to conventional treatment to reduce mortality in patients with septic AKI.

Keywords: Sepsis; Acute kidney injury; Continuous renal replacement therapy

Copyright © 2016 by The American Society for BioMedicine and BM-Publisher, Inc.

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