Genetic-hormonal pathways to non-squamous lung cancer: prognosticator and a therapeutic target

Research Article

American Journal of BioMedicine
Volume 11, Issue 2, Pages 57-64 | http://dx.doi.org/10.18081/2333-5106/2023.11/57

Mustafa A. Jaber, Kamel F. Al-Salmi, Yousif S. Hamid ^1*

*Correspondence author e-mail: yousifhamid33@gmail.com: ¹ Genetic Department, Medical School, Cario.

Received 12 January 2023 Revised 13 March 2023 Accepted 21 March 2023 Published 11 April 2023

Abstract

Lung carcinoma is one of the most commonly diagnosed cancers worldwide, and the leading cause of cancer deaths across the globe. The most recent epidemiological data indicate that lung cancer is attributed to 1 in 10 (11.4%) cancers diagnosed, and 1 in 5 (18.0%) deaths worldwide. Estrogen is speculated to play an important role in lung carcinogenesis. This review data indicates a significant role of the female sex hormone β-estradiol in the etiopathogenesis, clinical treatment, and prognosis of non-squamous lung cancer (NSCLC). Estrogen activity in the growth of NSCLC tumors has been confirmed by a number of studies, and lowering the level of estrogen hormones could have a positive effect on antitumor activity in this area.

Keywords:Non-squamous lung cancer; Estrogen; β-estradiol; Lung cancer survival

Copyright: © 2023 Hamid YS et al. This article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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APA

Chandra, S., and Vijayakumar, V. (2023). Laparoscopic ovarian electrocauterization in polycystic ovarian syndrome: outcome and Influencing factors. American Journal of BioMedicine, 11(1), 10-21.doi: 10.18081/2333-5106/2023.11/10

MLA

Sambit Chandra; Sujeet D. Vijayakumar. “Laparoscopic ovarian electrocauterization in polycystic ovarian syndrome: outcome and Influencing factors”. American Journal of BioMedicine, 11, 1, 2023, 10-21. doi: 10.18081/2333-5106/2023.11/10

HARVARD

Chandra, S., Vijayakumar, V. (2023). Laparoscopic ovarian electrocauterization in polycystic ovarian syndrome: outcome and Influencing factors. American Journal of BioMedicine, 11(1), PP. 10-21.doi: 10.18081/2333-5106/2023.11/10

VANCOUVER

Chandra, S., Vijayakumar, V. Laparoscopic ovarian electrocauterization in polycystic ovarian syndrome: outcome and Influencing factors. American Journal of BioMedicine, 2023; 11(1):10-21.doi: 10.18081/2333-5106/2023.11/10