Research Article DOI:10.18081/2333-5106/016-7/253-264 American Journal of BioMedicine Volume 7, Issue 3, pages 136-149 Received April 11, 2019; Accepted July 02, 2019; Published August 13, 2019 Naser Jawad Kadhim 1, Dhifaf Zaki Aziz 1, Maysaa Adil Hadi 2 Abstract DNA topoisomerases are ubiquitous, enzymes needed to control topological problems encountered during DNA replication, transcription, recombination and […]
Tag: DNA
Potential role of DNA repair in myocardial injury following ischemia and reperfusion
Ivor A. Benjamin¹, Toshio Higashi, Silvana Hrelia∗ Abstract Myocardial ischemia and reperfusion injury (I/R) is a common cause of myocardial injury following cardiac operations and intervention leading to an induction of oxidative stress, cellular dysfunction and depressed of cardiac function. DNA damage, including oxidative base modifications and physical DNA strand breaks, is a […]