Month: November 2014

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Endotoxemia-suppress cardiac function through dysregulation of mitochondrial biogenesis in mice model

Michele M. Bracale 1, Robyn B. Wonderge, Min Zhou, Evelyn G. Hazen*     Abstract Sepsis exaggerated proinflammatory response to infection that can progress to carries a significant cardiac dysfunction associated with morbidity and mortality. Mitochondrial biogenesis is involved in the control of cell metabolism, signal transduction, and regulation of mitochondrial reactive oxygen species (ROS) production. We […]

Role of CD70 in pathogenesis of ovarian cancer cell metastasis

Received January 14, 2020; Accepted April 27, 2020; Published May 21, 2020 http://dx.doi.org/10.18081/2333-5106/017-3/118-124 Jack L. Pincheira; Maria Wiseman; Florian K. Dinulescu Abstract This meta-analysis considers the previously published study that associated expression of CD70 by ovarian cancer cells with CD27-positive lymphocyte accumulation and poor patient prognosis. Here, a time-resolved approach to analysis has been used […]

Critical role of SEMA5A expression in invasion and metastasis of ovarian cancer cell

Dan G. Wang1, Nasser Ghaly Yousif2, Alaa Muhammad Sadiq3, Mary M. Schilling1, Alex J Danielson1*   Abstract Semaphorins are a large family of genes involved in the development and morphogenesis of the nervous system. SEMA5A has been reported as a bi-functional molecule, acting as both oncogene and tumor suppressor in different types of cancer. High […]