Hua Lee 1, Tong Sun, Mao Zhou, Yong Liu*     Abstract Stroke is a leading cause of mortality and morbidity worldwide, and hypertension is a major risk factor for both ischemic and hemorrhagic stroke. Although the relative effect of hypertension on stroke risk is similar in men and women, it is not established. Gender […]

Emily V Baker 1, David J Edwards, Rebecca  B Schulz, Michael  F Hirama* Abstract Viridans streptococci are a grouping of multiple streptococcal species which do not possess Lancefield antigens, are alpha-hemolytic, and result in infective endocarditis. Despite intensive care with antimicrobial therapy, the mortality has remained high for these infections and post infection squeal. All […]

Jingxian H Golemis 1, Laurie J Rudensky, Tania K Moltedo*   Abstract High-mobility group box 1 (HMGB1), a highly conserved non-histone chromosomal protein, was found to act as a potent proinflammatory cytokine and a mediator that participated in the development of systemic inflammatory response. Forty wild type C57BL/6 male (25-30gms) mice were randomly divided into […]