Month: August 2015

Regulatory mechanisms of IL-13 signaling pathway/role in normal gestation

  doi: 10.18081/2333-5106/015-08/468-480 American Journal of BioMedicine Volume 3, Issue 8, pages 468-480 Published: August 17, 2015 Marchil Carden, Maria Granger, Marchil G. Rovere, Amanda Bron, Jimmy Fukumoto Abstract It has become evident that IL-13 is a key mediator in the pathogenesis of many diseases. IL-13 receptors are expressed on human B cells, basophils, eosinophils, […]


High-mobility group box-1 protein induce inflammatory response after pulmonary injury

Jingxian H Golemis 1, Laurie J Rudensky, Tania K Moltedo*   Abstract High-mobility group box 1 (HMGB1), a highly conserved non-histone chromosomal protein, was found to act as a potent proinflammatory cytokine and a mediator that participated in the development of systemic inflammatory response. Forty wild type C57BL/6 male (25-30gms) mice were randomly divided into […]

Role of alkaline protease in activation of viridans streptococci complement system pathway

Emily V Baker 1, David J Edwards, Rebecca  B Schulz, Michael  F Hirama* Abstract Viridans streptococci are a grouping of multiple streptococcal species which do not possess Lancefield antigens, are alpha-hemolytic, and result in infective endocarditis. Despite intensive care with antimicrobial therapy, the mortality has remained high for these infections and post infection squeal. All […]