Month: October 2018

IL-32 promotes lung cancer cell invasion and metastasis through p38 MAPK signaling pathway: Cancer-associated fibroblast-derived

Sanjay Shete¹, Qing Kim¹′², Xiongyan Wu¹,  Xiaofeng Wang¹, Qiong Dong¹*     Abstract Lung cancer is the leading cause of cancer death in the United States and around the world. Recent studies indicate that cancer-associated fibroblasts (CAFs) are involved in tumor growth, invasion and metastasis, however, the underling mechanisms remain unclear.  In the present study, […]

Critical role of IL-32 invasion and metastasis of colonic cancer through upregulation of matrix metalloproteinase (MMP)-2

Chung Tsai¹, Hyo-Jin Kim, Jonthan Adriennea*      Abstract Interleukin (IL)-32 is proinflammatory cytokine, which has been shown to play an important role in cancer growth and metastasis. Here, we investigated whether the proinflammatory cytokine IL-32 may be involved in colonic carcinogenesis through upregulation of matrix metalloproteinase (MMP)-2. We are obtaining consent from all patients, […]

Cerebral blood flow and vasomotor reactivity assessment by using transcranial Doppler among Iraqi migraineurs-case control study

Hayder K Hassoun¹, Ahmed MH Almudhafar¹, Zuhair Allebban²*, Shehab Altemimi³, Hasanian A. AlSafar³, Mohamed Rhadi¹    Abstract The pathogenesis of migraine is still unknown, the hemodynamics and vascular hypothesis had been tested by many investigators using different methods including angiography, isotopes scan, PET and SPECT scans. In this study, we are assessing the use of […]