Month: October 2015

PXR mediated cardiac protection after sepsis through TLR4 modulation pathway

Seth F. Huska 1, Michelle H. Ade, Ainara Zhou, Roger Wentz, Cobley, Martin A. Roberts, James E. Lindberg, Mao Zhao*   Abstract Cardiac dysfunction is a vital component of multi-organ failure during severe sepsis. The primary function of pregnane X receptor (PXR) is to sense the presence of foreign toxic substances and in response up […]

Fetal descending aorta/umbilical artery flow velocity ratio in normal pregnancy at 36-40 weeks of gestational age

    Open Access Research Article   dx.doi.org/10.18081/2333-5106/015-10/674-685 American Journal of BioMedicine Volume 3, Issue 10, pages 674-685 Received July 03, 2015; accepted September 16, 2015; published October 30, 2015 Riyadh W Alessawia Abstract Doppler velocimetry studies of placental and aortic circulation have gained a wide popularity as it can provide important information regarding fetal well-being […]

Volume 7, Issue 3, 2019

Research Article Potential effects of gender disparity in downregulation of AKT after post-cerebral ischemia and reperfusion John M. Morrison, Claire B. Gibson, Zhan Wang, Daniel H. Klionsky Received: May 19, 2015; accepted: September 11, 2015; published: October 19, 2015; pp. 619-630 dx.doi.org/10.18081/2333-5106/015-10/619-630 Research Article Cardioprotective role of trans retinoic acid in trastuzumab-induced cardiotoxicity through modulation […]

Volume 7, Issue 2, 2019

Topic Review Role of SMAD/TGF-β signalling pathway in connective tissue diseases Xiao Li; Michael Bronner; John A. Ribeiro; Karen Oliveirar Received: March 02, 2015; accepted: August 19, 2015; published: September 10, 2015; pp. 534-544 dx.doi.org/10.18081/2333-5106/015-09/534-544 Clinical Case Malformations of the cranio-cervical junction: basilar impression Gonzalo Bertullo; Viviana Cabrera Received: June 02, 2015; accepted: August 04, […]

CIP2A overexpression up-regulates Akt signaling pathway in metastasis breast cancer cell

    Research Article   dx.doi.org/10.18081/2333-5106/015-10/658-673 American Journal of BioMedicine Volume 3, Issue 10, pages 658-673 Published: October 27, 2015 Chen Hsua, b, James H. Woodgetta, Tsung-Han Huanga, b, Trevor Penga, c, Patrick Wagnera, Gabriel Tyritzisa, John Shimizua Abstract Breast cancer, a major worldwide health threat, is considered to comprise a group of biologically heterogeneous diseases. […]