Seth F. Huska 1, Michelle H. Ade, Ainara Zhou, Roger Wentz, Cobley, Martin A. Roberts, James E. Lindberg, Mao Zhao* Abstract Cardiac dysfunction is a vital component of multi-organ failure during severe sepsis. The primary function of pregnane X receptor (PXR) is to sense the presence of foreign toxic substances and in response up […]
Month: October 2015
Volume 7, Issue 3, 2019
Research Article Potential effects of gender disparity in downregulation of AKT after post-cerebral ischemia and reperfusion John M. Morrison, Claire B. Gibson, Zhan Wang, Daniel H. Klionsky Received: May 19, 2015; accepted: September 11, 2015; published: October 19, 2015; pp. 619-630 dx.doi.org/10.18081/2333-5106/015-10/619-630 Research Article Cardioprotective role of trans retinoic acid in trastuzumab-induced cardiotoxicity through modulation […]
Volume 7, Issue 2, 2019
Topic Review Role of SMAD/TGF-β signalling pathway in connective tissue diseases Xiao Li; Michael Bronner; John A. Ribeiro; Karen Oliveirar Received: March 02, 2015; accepted: August 19, 2015; published: September 10, 2015; pp. 534-544 dx.doi.org/10.18081/2333-5106/015-09/534-544 Clinical Case Malformations of the cranio-cervical junction: basilar impression Gonzalo Bertullo; Viviana Cabrera Received: June 02, 2015; accepted: August 04, […]
Hydatid cyst of the heart: risk of heart block and cyst rupture
Thomas Sánchez-Serrano 1, Pedro J.Carmena, Manfred Tambini* Abstract The overall incidence of Echinococcus infection is 0.4 per 100,000 persons. Humans are an accidental intermediary host and can occur in any human organ or tissue, although most often found in the liver (60-70%) and lung (20-30%). Cardiac involvement of hydatid disease is uncommon (0.02-2%), and […]
New era in staging/treatment of multiple myeloma
EYa-Yun Shi 1, Wan-Yun Liu, Fu-Chao Wang* Abstract Multiple myeloma (MM) is a malignant disease of plasma cells with characteristic immune deregulation and represents 1% of all malignant diseases. The disease is characterized by clonal proliferation of plasma cells which may produce excessive amounts of monoclonal immunoglobulins that can be detected in serum and […]