The effect of topical finasteride in treatment of idiopathic hirsutism

Research Article
American Journal of BioMedicine Volume 3, Issue 9, pages 552-566
Published: September 20, 2015

Yahia Ibrahim Yahia, Nisreen J. Mohammed, Wisam A. Ameen


Hirsutism relatively is a common medical problem and an important influence on about 5-10% of women of reproductive age. Fifty five female shares in the study, seventeen of them did not continue the study, therefore we evaluated 38 females, aged 18-52 years old. In our study we compared pre-treatment and post-treatment for the color of the hairs and the hair removal frequency and the pain during hair removal for four groups which are good response group and moderate response group and mild response group and no response group, by subjective evaluation of all the patients noted a diminished rate of hair growth (fewer times needed for shaving) and a decrement in the density of hairs on the chin area and change in color of the hair but there was no significant difference between groups regarding hair color and there were highly significant difference in hair removal frequency before and after treatment (P<0.001) when we used finasteride cream 1% for 3 months. Six months of topically applied finasteride (0.5%) does not effect on number and thickness of facial hirsutism significantly. Despite lack of objective changes, on questioning, most patients in finastride group perceived a decrease in hair growth with time.

Keywords: Hirsutism; 5-α- dihydrotestosterone; TSH; FH; LH



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